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What should we pay attention to when purchasing veterinary drugs

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problems needing attention in purchasing veterinary drugs:
1. Select products produced by regular pharmaceutical factories with veterinary drug production licenses; The veterinary drug factory has passed the GMP acceptance; Select products whose packaging, labels and instructions meet the standards and Specifications issued by the Ministry
on the outer package of veterinary medicine, the words “veterinary” or “veterinary medicine” must be marked in an eye-catching position, and the label or instruction manual in the box should also be marked. Those not marked can not be used as veterinary drugs. The outer packaging box of veterinary drugs or the instructions in the box shall clearly indicate the trademark name, veterinary drug name, enterprise name, production address, communication mode, highly toxic or external drug mark, main ingredients, pharmacological action, indications (use), usage and dosage, adverse reactions, precautions, withdrawal period, packaging specification, medication contraindications, storage conditions, validity period, etc
2. Select the qualified products in the veterinary drug product quality notification of the animal husbandry and Veterinary Bureau of the Ministry of agriculture; Select products with advertising approval number reviewed by the province and Ministry; Select products recommended by the Ministry and China Animal Protection Association or products of enterprises with reliable quality
veterinary drug products must be marked with the approval number. The veterinary drug approval number shall be valid for 5 years and shall be invalidated upon expiration of the original veterinary drug approval number. If the approval number used exceeds the period of validity, veterinary drugs are regarded as fake drugs. The veterinary drug approval number must be in accordance with the unified numbering format stipulated by the Ministry of agriculture. If the document number is used or replaced by other numbers, it shall also be regarded as a fake drug. Product batch number is a group of numbers or letters plus numbers used to identify the “batch”. Generally, it is composed of two digits of the date of production plus the production batch. If there is no product batch number, it shall not be used. For a considerable number of veterinary drugs, the validity period or expiration period is also specified, and the number of years of validity is marked, which is calculated from the production date (subject to the product batch number). Sometimes, it is also marked with specific year, month and day, and the expiration period is mostly marked with specific year, month and day. If the expiration date is exceeded or has reached the expiration date, it is an expired drug. It should not be used again even if there are no visual quality problems
3. You cannot buy (use) illegal or prohibited drugs stipulated by the Ministry of agriculture
after unpacking the outer packaging of veterinary drugs, pay attention to check whether the inner packaging box (bag) is attached with instructions and product quality certificate. The certificate shall have the special seal for quality inspection of the enterprise, the signature and seal of the quality inspector and the packing date. If there is no product certificate, it is not the product of a regular manufacturer and cannot be used. Checking the internal packaging of veterinary drugs can also see whether veterinary drugs are qualified. If it is sealed with plastic bag, pay attention to check whether the seal is tight. For those sealed with glass bottles, pay attention to check whether the bottle cap is sealed, whether there are looseness and cracks, and whether the bottle stopper has obvious pinholes. If the ampoule is used for packaging, pay attention to check whether the ampoule is clean, whether the head is round, and whether the words sprayed on the ampoule are clear and complete. Veterinary drugs with any packaging problems cannot be purchased and used. Some drugs need to be sealed and protected from light, such as iodine tincture, cresol soap, formaldehyde, hydrogen peroxide, etc. if they are packaged in colorless and unshaded recycled infusion bottles, they cannot meet the storage requirements and cannot be used. In addition, tablets and premixes that need to be kept away from light, if packaged in colorless plastic bags, are prone to degradation and other deterioration, which is also unqualified.

at present, the veterinary drug market in rural areas is not very standardized, and the sources of veterinary drugs are relatively complex. If farmers are careless, they may use fake drugs, inferior drugs, expired drugs or obsolete drugs. Therefore, farmers must be careful when purchasing, using and preserving veterinary drugs. In order to increase the farmers’ rights protection knowledge of veterinary drugs and protect the interests of the majority of farmers, when purchasing veterinary drugs, we should pay attention to the following aspects

(1) to purchase veterinary drugs from veterinary drug stores with veterinary drug business license, try to stay away from drugs with extremely low price and poor packaging. When purchasing veterinary drugs, businesses must be required to issue bills

(2) identify the package. On the outer package of veterinary drugs, the words “veterinary” or “veterinary drugs” must be marked in an eye-catching position, with instructions attached. The contents of the instructions can also be printed on the label. The label or instruction manual must indicate the trademark, veterinary drug name, specification, enterprise name, address, approval number, product batch number, highly toxic drug mark, and indicate the main components and content, purpose, usage and dosage, toxic and side effects, indications, contraindications, validity period, precautions and storage conditions of veterinary drugs. The label or instructions in the box shall also be indicated. Those not marked can not be used as veterinary drugs. Check whether the veterinary drug manufacturer has passed the GMP standard of the Ministry of agriculture and whether it has a crude drug production license. The label and instruction manual of a legal veterinary drug manufacturer shall indicate the production license number. Any veterinary drug not indicated or produced by an unapproved unit must be a fake veterinary drug product

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(3) check the product approval number. First check whether the product has an approval number, and then check whether the format of the approval number is correct. Veterinary drug products must be marked with the approval number, and the production enterprises that have passed GMP certification must also be clearly marked. The veterinary drug approval number shall be valid for 5 years and shall be invalidated upon expiration of the original veterinary drug approval number. If the approval number used exceeds the period of validity, veterinary drugs are regarded as fake drugs. The veterinary drug approval number must be in accordance with the unified numbering format stipulated by the Ministry of agriculture. If the document number or other number is used to replace it and pretend to be the veterinary drug production approval number, the product shall be regarded as a product without approval number, and it shall also be regarded as a fake drug

see whether the approval number is within the validity period (the validity period is 5 years). If it is not within the validity period, it is a inferior veterinary drug. The four Arabic numerals marked in the brackets in the approval number are the year when the approval number is approved. If the year marked with the production batch number (i.e. production date) shall not exceed the approval year of the approval number plus 5 years

① abbreviation of veterinary drug category. The category of drug additives is abbreviated as “veterinary drug additive”; The categories of serum products, vaccines, diagnostic products and micro ecological products are abbreviated as “new words of veterinary drugs”; The categories of Chinese
medicinal materials, Chinese patent medicines, chemicals, antibiotics, biochemical drugs, radioactive drugs, topical pesticides and disinfectants are referred to as “veterinary drugs” for short

② the year number is represented by four digits, that is, the year when the product approval number is issued

③ the serial number of the province where the enterprise is located is represented by two Arabic numerals, which shall be stipulated and announced by the Ministry of agriculture

④ the enterprise serial number is sorted by province, expressed in 3 Arabic numerals, and announced by the Ministry of agriculture

⑤ the number of veterinary drug varieties is represented by 4 Arabic numerals. The drug approval number is stipulated and announced by the Ministry of agriculture. The unified number format stipulated by the Ministry of agriculture is veterinary drug (year) ××)×× Pharmaceutical Factory No ×× Variety number

all veterinary drugs sold and used in China must be mainly in Chinese. The approval number of veterinary drugs can be queried on the Chinese veterinary drug information website. Website: http: //

(4) check the product specification. Check whether the specifications marked on the label are consistent with the actual drug, mainly to see whether the marked loading is consistent with the actual loading

(5) check the Executive Standards of veterinary drug products. Veterinary drug standards shall be in accordance with national standards (Chinese Veterinary Pharmacopoeia, ministerial standards issued by the Ministry of Agriculture) or provincial local standards. If the ingredients of veterinary drugs do not meet national standards or provincial local standards, they are counterfeit drugs

(6) check the validity period of veterinary drugs. Identify the “batch number”. Product batch number is a group of numbers or letters plus numbers used to identify the “batch”. Generally, it is composed of two digits of the date of production plus the production batch. If there is no product batch number, it shall not be used. A considerable number of veterinary drugs also specify the period of validity or expiration. The period of validity marked with the number of years is calculated from the production date (subject to the product batch number). Sometimes, it is also marked with the specific year, month and day. The expiration period is mostly marked with the specific year, month and day. Expired veterinary drugs are those that exceed the expiration date or have reached the expiration date. They should not be used again even if there are no visual quality problems

(7) check the “certificate” of veterinary drugs. After unpacking the outer packaging of veterinary drugs, pay attention to check whether the inner packaging box (bag) is attached with instructions and product quality certificate. The certificate shall have the special seal for quality inspection of the enterprise, the signature and seal of the quality inspector and the packing date. If there is no product certificate, it is not the product of a regular manufacturer and cannot be used

(8) check whether it is a veterinary drug prohibited or eliminated by the state. The veterinary drugs prohibited from use in the catalogue of abolition of local standards for veterinary drugs announced by the Ministry of agriculture No. 560 are fake veterinary drugs, which are prohibited from trading and use

(9) check the “packaging” of veterinary drugs. Checking the internal packaging of veterinary drugs can also see whether veterinary drugs are qualified. If it is sealed with plastic bag, pay attention to check whether the seal is tight; Check whether there are cracks in the bottle cap and whether the bottle cap is loose, and whether there are obvious cracks in the bottle cap; If the ampoule is used for packaging, pay attention to check whether the ampoule is clean, whether the head is round, and whether the words sprayed on the ampoule are clear and complete. Veterinary drugs with any packaging problems cannot be purchased or used. Some drugs need to be sealed and protected from light, such as iodine tincture, cresol soap, formaldehyde, hydrogen peroxide, etc. if they are packaged in colorless and unshaded recycled infusion bottles, they cannot meet the storage requirements and cannot be used. Similarly, tablets and premixes that need to be kept away from light are also unqualified if they are packaged in colorless plastic bags, which are prone to degradation and other deterioration. Check whether the boxed injection has broken bottles and empty bottles, and whether the weight of the original powder is insufficient

(10) pay attention to the internal quality of veterinary drugs, such as whether the package is caked, whether the injection is abnormal and discolored, and whether the original powder is obviously damp. Identification of appearance quality of different dosage forms

① tablet: the appearance should be complete and smooth, the color should be uniform, the hardness should be appropriate, there should be no spots, black spots, no broken, sticky, discolored, no abnormal odor, otherwise it should not be used

② powder injection: mainly observe whether there is bottle sticking, discoloration, caking, deterioration, etc. in case of the above phenomena, it cannot be used

③ powder (including feed additives): the powder should be dry and loose, with uniform particles and consistent color, without moisture absorption, caking, mildew, sticky and other phenomena

④ water injection: the appearance liquid must be clear and free from turbidity, discoloration, crystallization, bacteria and other phenomena, otherwise it cannot be used

⑤ traditional Chinese medicine: it mainly depends on whether it has moisture absorption, mildew, moth, mouse bite, etc. in case of the above phenomena, it is not suitable to continue to use

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